In case it's not already apparent, I'm on a blogging break at the moment, while I work on some big projects.
Yes, including a book.
In the meantime, I've gone ahead and shut off comments for now, as an overwhelming majority of the incoming comments are just attempts at spam. As I hand-approve every comment that goes up, none of that spam has gotten through. My spam-blocking is mighty.
If any interesting talk videos or TV stuff rolls around, I'll post, so don't take me off your RSS list. And I will get back to blogging in the weeks or months to come.
Email still works, and if you can't stand to be without my textual voice, I'm on Twitter as @cascio.
Is something still meaningful and true, even when it's been turned into a marketing slogan?
(Spotted in London, in the window of a brand marketing agency.)
I was asked awhile back to put up a list of my favorite pieces; I've finally gotten around to doing so (and, in the course of the clean-up, making some long-planned modifications to the layout of the OtF home page).
However, I am well aware that what I found most interesting or fun to write may not match with what other folks particularly liked.
So -- what's wrong with the list? Is there a piece that you're just stunned I didn't include? Is there an item that you're baffled as to why I thought it was worth reading in the first place?
Tell me.
If you already understand what's happening with the Venter Institute synthetic genome announcement, and just want to see my response, here's the money quote from the end of the previous post:
One suggestion that we know is possible, because a variation appeared in the Venter announcement: all synthetic genomes should be signed. According to Wired:
“They rebuilt a natural sequence and they put in some poetry,” said University of California at San Francisco synthetic biologist Chris Voigt. “They recreated some quotes in the genome sequence as watermarks.”What Voigt refers to as a "watermark" should instead be thought of as a "DNA signature." We should require that all synthetic genomes include something like this, unique sequences following a designated pattern, identifying the organization behind the genome, the lab responsible, the date, and any other useful bits of information. Multiple copies should appear throughout the synthetic genome, so it doesn't get mutated away.
That way, if something unexpected happens, we know whom to talk to.
The Venter Institute announcement that it had successfully crafted the first self-replicating synthetic organism caused quite a stir, even among people who are otherwise pretty jaded about emerging tech.
It's useful to understand exactly what is -- and what isn't -- going on here.
Where we are:This is a moderately big deal, but only that; it's a stepping-stone to a real big deal down the road. What the Venter Institute has done is synthesize a genome that reproduces the genome of an existing organism, then insert that genome into the body of an existing cell, replacing its own DNA. That cell was then able to self-replicate, indicating that the synthetic DNA copy was sufficiently complete.
"Synthetic" here doesn't mean artificial, by the way. The DNA of the synthetic genome comprises the same base pairs and nucleotides as a natural genome, but was synthesized in the lab rather than replicated from an earlier cell. The best analogy I can think of is if, rather than copying the MP3 of your favorite song, you pulled together a really sophisticated music creation application and reproduced the song yourself, exact in every detail. It's the same, but a synthetic version.
If that sounds like a lot of work to get something that is essentially the same as the natural/original version, you're right. But this step was never the real goal -- it's just preparation. The real goal is to create an entirely novel life form, comprising both entirely new DNA and an entirely new cell. That's still to come.
Where we aren't:The synthetic genome created by the Venter Institute is a streamlined version of the original Mycoplasma mycoides bacteria, containing enough of the original code to replicate and function as M. mycoides. Adding transgenic features -- that is, genetic material copied from non-M. mycoides species -- should be fairly straightforward, as it's essentially doing standard bioengineering.
In principle, this should actually be somewhat safer than current transgenic biotech, as they'll have much more precise control over the engineered genomes.
The ultimate goal would be to create an entirely new bacterial species by creating genes that do new things, or by combining diverse known DNA sequences to create a functional, replicating bacteria that doesn't mimic any existing species. This will be hard, but clearly not impossible.
The bonus goal:
The cell in which the synthetic DNA is housed already existed, but with different DNA (it was the cell of a related species of Mycoplasma). One likely future step will be to create an entirely synthetic cell by throwing together the right set of proteins in just the right way. Like the latest breakthrough, that will undoubtedly start out by simply reproducing an existing cell structure. Ultimately, they'll want to create cellular bodies that have novel features, such as (conjecture here) additional mitochondria for added power.
Where we go:So what does this all mean?
The idea is to turn bacteria into microscopic machines, carrying out designated tasks in massively-parallel operations. Given the extreme range of things that bacteria can do in nature, the extent to which bacterial machines might be used is pretty staggering, particularly concerning environmental response. This would be a perfect platform for methanotrophic remediation of melting permafrost, for example; the Venter folks are already talking about building synthetic bacteria to do carbon capture. Biofuels are also high on the agenda.
The big concern about synthetic biology is the potential for the creation of hazardous materials -- aggressive, infectious bacteria, for example. We should also consider, at the same time, its biomedical potential. Are there ways of delivering drugs via synthetic bacteria?
One advantage of the big splash this relatively modest development has made is that it opens up the possibility of laying out the parameters of what ethical, responsible management of this technology would look like before have to confront its fully-developed form.
Should we require a "shut-off" gene in any novogenic organism, one that kills the cell if certain conditions are (or aren't) met? A reproduction-limiting set of genes that only permits replication in the presence of a rare chemical? Public registration of all novogenic genomes?
One suggestion that we know is possible, because a variation appeared in the Venter announcement: all synthetic genomes should be signed. According to Wired:
“They rebuilt a natural sequence and they put in some poetry,” said University of California at San Francisco synthetic biologist Chris Voigt. “They recreated some quotes in the genome sequence as watermarks.”What Voigt refers to as a "watermark" should instead be thought of as a "DNA signature." We should require that all synthetic genomes include something like this, unique sequences following a designated pattern, identifying the organization behind the genome, the lab responsible, the date, and any other useful bits of information. Multiple copies should appear throughout the synthetic genome, so it doesn't get mutated away.
That way, if something unexpected happens, we know whom to talk to.
I'm honored to have been asked to serve on the advisory council for LAUNCH, a group looking to support innovative ideas for sustainability. Sponsored by NASA, the US Department of State, US Aid for International Development, and Nike(!), LAUNCH is intended to give good ideas the assistance -- financial and otherwise -- necessary to move from concept to plan to implementation.
LAUNCH will identify 10 innovative, often disruptive world-class ideas, technologies or programs that show great promise in making tangible and impactful progress for society in each of the key challenge areas. These innovators will be invited to be part of the LAUNCH Sustainability Forum which is a high-level impact event where they present their innovative ideas to LAUNCH and engage in a collaborative discussion.The event however, is just the starting point, post-event the Innovators will become part of the LAUNCH Accelerator, an on-going effort which utilizes the collective power of the networks, resources and expertise of the LAUNCH organization to create and execute an action plan accelerating them from where they are to where they need to be to successful have a positive impact on global sustainability.
The first meeting will be about water-related innovations; you can see the list of ideas we'll be talking through here.
My fellow LAUNCH Council members are all brilliant and insightful, and I'm gobsmacked to be a part of this group.
As you might know (especially if you've read my bio), I went to college at the University of California at Santa Cruz, receiving a double-BA in History (with a focus on 20th century revolutionary movements) and Anthropology (with a focus on human evolution). UCSC was a terrific place to get an education, due to (at the time) its use of narrative evaluations rather than letter grades, the deep commitment on the part of the faculty to undergraduate education, and its general spirit of enlightened experimentation. Although UC Santa Cruz has changed over the 22 years since I left, I still have real affection for the place.
So when UCSC contacted me about speaking at an upcoming event, I jumped at the opportunity to give something back.
On Saturday, April 17, I'll be one of the three featured speakers at what they're calling the "Intellectual Forum," part of the 2010 Reunion Weekend "Day by the Bay."
What does the future look like?Three UCSC alumni explore the next generation of communities, work and health care, offering fascinating insights into the way we’ll live our lives:
Jamais Cascio (Cowell, anthropology and history ’88)
Writer, leader, and visionary, Jamais will share scenarios of the future that cross the boundaries of technology, the environment, and society. Research Fellow, Institute For The Future. Named by Foreign Policy as one of the top 100 global thinkers and a "moral guide to the future."
Shannon Brownlee (College Eight, biology ’79)
Nationally known writer and essayist whose book, Overtreated: Why Too Much Medicine is Making Us Sicker and Poorer was named the best economics book of 2007 by the New York Times.
David Bank (Oakes, politics ’82)
Vice President, Civic Ventures. A veteran journalist, Bank was a reporter for The Wall Street Journal for nine years, covering Silicon Valley and the software industry. His book, Breaking Windows: How Bill Gates Fumbled the Future of Microsoft (Free Press) was named one of the "Best Business Books of 2001" by the Harvard Business Review
The event is free, although you'll need to register. And don't blame me for what they're calling it.
On Monday, April 19 (yeah, just two days after the UCSC thing), I'll be speaking at Social Business Edge in New York City, a new (and hopefully recurring) event looking at the intersection of business innovation and social media.
Certainly what is going on today is more than just social media marketing, limited to marketing and community outreach efforts. Some of the leading thinkers in this area believe that we are at the start of something much larger than a retake on marketing. We are seeing a rethinking of work, collaboration, and the role of management in a changing world, where the principles and tools of the web are transforming society, media, and business. The mainstays of business theory — like innovation, competitive advantage, marketing, production, and strategic planning — need to be reconsidered and rebalanced in the context of a changing world. The rise of the real-time, social web has become one of the critical factors in this new century, along with a radically changed global economic climate, an accelerating need for sustainable business practices, and a political context demanding increased openness in business.Assembled (and hosted) by my friend Stowe Boyd, Social Business Edge includes a pretty good variety of speakers. Stowe has decided to do this in something of a "talk show" format, so use of powerpoints will be limited, and the presentations will be more conversational than formal.
The event isn't free, but it is pretty reasonably priced for something like this. If you're in the area, and are interested in the future of social media, I think you'll find this quite valuable. Hope to see you there!
I spent the last three days at the Kennedy Space Center, for the inaugural meeting of the LAUNCH organization. We talked water, and saw some pretty interesting -- and occasionally remarkable -- innovations and proposals. I'll have more to say about them in a bit, but for now...
I grew up a space geek (and dinosaur geek, etc.), so the visit to KSC was a welcome reminder of those feelings. We didn't just get the basic tour; we actually got some behind-the-scenes stuff that was just amazing (and, because the shuttle program is ending soon, won't be replicable for much longer). We got to go into the shuttle processing facility, where one of the shuttles (in this case, Endeavor) gets cleaned and fixed and otherwise readied for an upcoming launch. This meant walking around beneath the shuttle, right below the heat-resistant tiles (and occasionally spotting when one of them needed to be replaced).
The photomontage at right was taken of the shuttle Discovery, set to launch in the next few weeks; I took the pictures while we were parked in the blast zone, where flames from the engines go in the initial moments of take-off. Anything in this zone would be instantly incinerated -- and even the fencing a few hundred yards behind us was bent and blackened.
(You can see all of the pictures I've made public at this link on Flickr.)
Even the normal tour items were pretty amazing -- the Saturn V rocket engines, the actual Apollo mission control consoles, and a piece of the Moon.
That you can touch.
As astounding as it all was, there was a subtle melancholy there, as well. The Constellation program to return to the Moon was canceled in the most recent NASA budget (with the money redirected to more robotic missions and long-range research, so I'm actually in full approval), and the engineers we spoke to all made a point of mentioning it unhappily.
But beyond that was the recognition that the massive rockets and space-stations programs are the apotheosis of 20th century engineering. These are artifacts of yesterday's version of tomorrow, the mechanistic urge on an unthinkable scale. And such remarkable, complex systems are ultimately tied to a worldview and process that celebrates the centralized and the controlled in an era that is increasingly neither.
The future of human civilization, in the end, lies in space. But getting there, and staying there, will look nothing like the heady visions of Apollo.
A Survival Guide to Geoengineering, my essay for Momentum, the journal of the University of Minnesota's Institute on the Environment, is now available online and via PDF. It's an exploration of what would be necessary to reduce the risks associated with geoengineering, if (or, sadly, when) it gets deployed. This essay served as the basis of the talk I gave at the State of Green Business Forum last month.
The first part of the essay is a recap of the main issues around geoengineering -- the kinds of proposals out there, the uncertainties involved, and the political dilemmas. But the real focus is the list of five key steps that I believe to be mandatory to steer us away from the worst potential results of geoengineering:
Interestingly, when I gave the talk in February going over these ideas, the last is the one that I got the most push-back on. I suspect that, once real mechanisms for monitoring and managing global climate systems are in place, non-state projects could be useful and warranted. For now, however, it seems clear that non-state groups acting independently are more likely to lead to inter-state disputes than any persistent moderation of temperatures or carbon.
My latest Fast Company piece went up last night, in commemoration of World Water Day 2010. This was the perfect opportunity to talk a bit about my time at the LAUNCH inaugural event, which focused on -- surprise -- water. In the essay, I talk a bit about three of the ten innovative ideas we got a chance to explore at the LAUNCH meeting. Here's one:
Dutyion Root Hydration System, a mouthful of a name for something that's actually pretty remarkable. The system takes a specialized form of hydrophilic plastic and converts it into heavy-duty tubes suitable for below-ground irrigation. If you run saltwater (or similarly brackish/unusable water) through the tubes, the plastic wicks the water out as vapor, permeating it into the soil, which can then support many kinds of food crops and trees. That is, this plastic would let you irrigate orchards and farmland with sea water.There are still plenty of questions, most critically about how long the plastic lasts and how to bring down production cost (it's not cheap, at present), but the utility of something like would be enormous. Test uses in the Middle East have already shown quite a bit of promise; one use that could be of particular value would be to maintain trees to fight desertification.
This was actually the first item we talked about at LAUNCH, and it really set the tone for the meeting. A technology in the early stages of development, with some good test results already available, and with incredible potential for transforming the landscape. The pilot projects really underscore just how powerful this kind of tech might be: rows of fruit trees growing in the sands of Abu Dhabi, watered only by seawater pumped from the Gulf through the dutyion tubes. As I say at the end of the Fast Company post:
This month has proven to be hellaciously swamped, but that's no excuse for disappearing like that.
I'm still on the hellaciously swamped clock until the end of April, however. One of the things on my checklist is a very short trip to NYC to speak at the Social Business Edge conference. My topic:
Now to figure out what that means...
If you can't make it to NYC, you can still follow the livestream of the Social Business Edge conference here. It's a good set of speakers, and I'm really looking forward to hearing what everyone else has to say.
I've also been asked to speak at the Activate Summit 2010, in London. It's put on by The Guardian, and looks to be an effort to put together a UK-based TED-type event. It's definitely a TED-class set of speakers on the roster this time around, so it should be quite fun.
It turns out that I was in NYC a bit over a week ago, filming an interview for "Sci-Fi Science: Physics of the Impossible," a show on the Science Channel in the US, and ITV in the UK. My bits won't run until the Summer. It seems to be broadly similar to the "That's Impossible" show I popped up in last year, only this one is hosted by an honest-to-goodness scientist: Michio Kaku.
While Dr. Kaku didn't conduct the interview, he was there for it, and he and I had an informal lunch afterwards. Let me say, talking about the Fermi Paradox, the origins of the universe, and boiling spacetime(!) with one of the leading thinkers in string theory was pretty damn cool.
My talk at Social Business Edge went very well -- I'll have video as soon as it's available.
2010-04-19 21:35:15: @cascio just said like five excellent things in 2 sentences and i can't keep up. #sbenyc #smartpeoplerule via randomdeanna (Deanna Zandt)IFTF Ten-Year Forecast meeting starts tomorrow evening.
I speak at LIFT10 in less than two weeks, and have been asked to speak at Activate2010 in London on July 1.
Fast Company Earth Day post at Fast Company: "Earth Day 2020" -- a set of four scenarios of what we might be doing in 10 years... Scenario #2: "Signs of Desperation"Also, Futures Thinking: A Bibliography at Fast Company.
Other Articles "Bouncing Back: Building a Resilient Tomorrow," for the Swiss Federal Institute of Technology, Zurich, International Relations and Security Network. At the core of the resilience concept is a simple argument: Failure happens, so we need to be ready. Yet strategies that depend upon complete, ongoing success – and that collapse under pressure – are distressingly common. We saw it in Iraq war planning that paid insufficient attention to the potential for post-war instability and in financial models that assumed that home prices only go up; we see it now in environmental arguments that assert that our only option is an immediate, complete cessation of carbon emissions. This way of thinking – call it the “aspirational” model – has us ask one big question: “What can we do to maximize our results?” When everything works as desired, this approach can be quite efficient and sometimes enormously successful.But what if things don’t go as planned?
"The Potential and Risks of Geoengineering," for The Futurist (World Future Society) -- part of the "20 Forecasts for the Next 25 Years" series.
It’s hard to exaggerate the sheer complexity of the situation. If the great obstacle to our continued survival and prosperity as a species were “just” global warming, achieving success would be tricky but doable. The challenge we face is global warming plus resource collapse plus pandemic disease plus post-hegemonic disorder plus the myriad other issues.Nonetheless, there are reasons for optimism.
(Some of the essay might sound familiar; I was encouraged to go ahead and re-use bits to streamline the process of writing it.)
...whew...
Last week, Kyle Vandercamp, an atmospheric scientist, blew the whistle on a rogue geoengineering project funded by billionaire Harrison Wyld. Vandercamp was a senior scientist at the Bluebird Lab, and managed to get ahold of some pretty damning documents laying out the extent of what the Bluebird project intends to do.
In short, Bluebird was supposed to be a research project looking at what geoengineering would entail, but Vandercamp says that they're actually looking at a near-term full-scale deployment.
Here's the Bluebird website, which apparently had to go public early because of Vandercamp's leak. This is their promo video:
Stop Bluebird is a web-driven campaign to push back against this geoengineering experiment. Documentary filmmaker Juanita Monte is helping to organize this effort, so the campaign is pretty video-focused.
Here's Monte's video summary of what just happened:
Here's Vandercamp's website, as well as the Stop Bluebird website.
Or, maybe not.
Bluebird is actually an "alternate reality game," put together by the Australian Broadcasting Company. Here's the home page for the game.
I'm pleased to say that the producers of Bluebird contacted me last year to serve as an advisor for the game, and they even had me write a few pieces for the project. If the script for the official Bluebird video above sounds familiar, it should -- I wrote it. (Ken Caldeira was another advisor, so I feel pretty confident about the science of the game.)
As with any near-term science fiction, events kept catching up with the alternate reality we were trying to create. I think the folks at ABC struck a good balance, though, and I like the storyline that they've constructed (and trust me -- what's available now is just the beginning).
It's a web-based ARG, so you don't have to be based in Australia to play. Give it a shot -- and let me know what you think!